Ionis Pharmaceuticals, Inc.

Save the date for our Q2 2025 earnings webcast. Register now and tune in live on July 30 at 11:30 am ET: https://lnkd.in/eetfK76F

For HCPs: Familial chylomicronemia syndrome (#FCS) is a genetic disease that is often challenging to recognize and can be underdiagnosed. Diagnosis often begins with a clinical suspicion, based on elevated triglyceride levels that are refractory to lipid lowering therapies, as well as other physical symptoms like acute pancreatitis.     Established scoring criteria, such as the North American FCS (NAFCS) score, can also be used to estimate a patient’s likelihood of FCS on the basis of common clinical and laboratory tests.     Because clinical clues can overlap with other conditions, genetic confirmation can also help accurately diagnose FCS and guide appropriate care. Early, accurate diagnosis can help patients avoid years of misdiagnosis and ineffective treatment.     To learn more about available resources to assist diagnosis, visit https://lnkd.in/eDc-rNGb.  

We’re on the ground in Baltimore with the hereditary angioedema (#HAE) community at the 2025 National Summit, hosted by the Hereditary Angioedema Association - HAEA.    Hearing directly from the HAE community about their experiences inspires our work, and we’re grateful for the opportunity to connect with so many of you. If you’re attending the summit, stop by the Ionis booth to say hello!    Are you or a loved one living with HAE? Check out HAEVNhub.com to connect with others and find helpful resources.  

Inspiring and engaging diverse youth and students with STEM learning opportunities is a core focus for Ionis. This year, more than 100 students attended our three signature NEXT STEM Education on-site events. Most recently, our NEXT STEM employee volunteers hosted first-generation, college-bound high school juniors and seniors from  San Diego Squared (SD2) and Salk Institute for Biological Studies. During their visit, students learned about our groundbreaking RNA technology, toured our labs, joined a hands-on homeostasis experiment and connected with Ions during an engaging career panel.  Thank you to all our partners and Ion volunteers for making these 2025 STEM events a success. We’re excited to keep growing our STEM programs in 2026 to nurture the next generation of science leaders!

It’s been a #PrideMonth full of celebration, reflection, education and support for #LGBTQIA+ Ions and allies. We rounded out our Pride programming with an exploration of gender through history, endocrinology and neurology, led by Valentin Berdeja (they/them), research associate II, and with a session fostering understanding and cultural competency around gender diversity for parents—a collaboration between our Parent Network and LGBTQIA+ ERGs. Thank you to everyone who contributes to our culture of inclusion all year long! 

Today, with Biogen, we shared positive interim results from the Phase 1 study of our investigational ASO for the potential treatment of spinal muscular atrophy (#SMA). Read more: https://lnkd.in/echeFQVm

HCPs, we’re one week out from the National Triglyceride Alliance’s webinar on diagnosing and managing severe hypertriglyceridemia (sHTG). We’re proud to be a sponsor and encourage you to register for real-world case studies, valuable clinical insights and the chance to ask Dr. Seth Baum and Dr. James Underberg your questions live. https://lnkd.in/et2-rhzN

Living with a rare disease like hereditary angioedema (#HAE) can be difficult. Take a breather and listen to this month’s HAE Speaks podcast episode with Hereditary Angioedema Association - HAEA to learn tips for quieting your mind from Danielle and Kia, patient education managers at Ionis, and Anne, a certified mindfulness meditation teacher. 

Our 2025 undergraduate and graduate internship program is underway! Working with mentors across Ionis, our interns are getting industry experience that complements their educational pursuits, contributing to meaningful projects and creating valuable connections. Join us in welcoming the next generation of scientists, researchers and biotech professionals! Learn more about our intern program: https://lnkd.in/ebsUgz2C

Sláinte! Earlier this month, Ions from across Europe came together at our Dublin office for two days of team building, learning and connection. Donal Murray, vice president, GMP Quality and head of Europe, reflected, “These moments allow us to strengthen our relationships, share ideas more freely and remind ourselves of the shared purpose that drives us every day.” Thanks to our Dublin Ions for hosting this special opportunity for development and fun!